Trichotillomania treated with n-acetylcysteine

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N-acetylcysteine in Treatment of Trichotillomania

Evidence suggests that abnormalities in the corticostriato-thalamic-cortical circuits are one of the key factors underlying the pathophysiology of OCDR, including trichotillomania. Particularly, orbitofrontal cortex, anterior cingulate and ventromedial striatum hypermetabolism has been linked to OCD (Ahmari et al., 2013). Glutamate is the primary neurotransmitter within the cortico-striatothala...

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Trichotillomania: a good response to treatment with N-acetylcysteine*

Trichotillomania is considered a behavioral disorder and is characterized by the recurring habit of pulling one's hair, resulting in secondary alopecia. It affects 1% of the adult population, and 2 to 4.4% of psychiatric patients meet the diagnostic criteria. It can occur at any age and is more prevalent in adolescents and females. Its occurrence in childhood is not uncommon and tends to have a...

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N-Acetylcysteine, a Glutamate Modulator, in the Treatment of Trichotillomania

Context Trichotillomania is characterized by repetitive hair pulling that causes noticeable hair loss. Data on the pharmacologic treatment of trichotillomania are limited to conflicting studies of serotonergic medications. N-acetylcysteine, an amino acid, seems to restore the extracellular glutamate concentration in the nucleus accumbens and, therefore, offers promise in the reduction of compul...

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N-acetylcysteine in trichotillomania as an alternative treatment option

We aimed to examine trichotillomania (TTM), a rarely seen disorder, and N-acetylcysteine (NAC), an agent used as a treatment option, in the light of literature in the present study. Trichotillomania is the compulsive urge to pull out one’s own hair persistently and leading to noticeable hair loss. Contrary to what is expected, it is a more frequently detected disorder characterized by compulsiv...

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Pseudoporphyria induced by dialysis treated with oral N-acetylcysteine.

Pseudoporphyria is a rare bullous dermatosis that clinically and histopathologically is similar to porphyria cutanea tarda. It mainly affects patients with chronic renal failure on peritoneal dialysis or hemodialysis. Medications can also be involved in the etiology. Diagnosis and management of this condition is a challenge for dermatologists. The authors report a case of pseudoporphyria relate...

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ژورنال

عنوان ژورنال: Psychiatry and Clinical Psychopharmacology

سال: 2018

ISSN: 2475-0573,2475-0581

DOI: 10.1080/24750573.2018.1472907